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Research Overview

The Zhang Lab studies cardiac diseases linked to loss of endothelial cell identity.

Major research directions:

  1. Single cell techniques to track cell lineage specification and cell identity transition in HLHS disease
  2. Investigate cell identity regulation in HLHS disease to facilitate development of therapeutic strategy
  3. Investigate the role of endothelial cell dysfunction in heart failure

Research Background

Dr. Zhang received postdoctoral training in cardiovascular epigenetics with a focus on endothelial cell identity regulation at The Methodist Hospital Research Institute and Weill Cornell Medical School, where she became an Assistant Professor.

Publications

  1. Publisher Correction: Epigenetic landscape reveals MECOM as an endothelial lineage regulator. Nat Commun. 2023 May 18; 14(1):2842. View Abstract
  2. Epigenetic landscape reveals MECOM as an endothelial lineage regulator. Nat Commun. 2023 04 25; 14(1):2390. View Abstract

Contact Lili Zhang