Information

Related Research Units

Cardiology Research
Psychiatry Research

Research Overview

Dr. Calderon's research focuses on the consequences of prenatal and infant insults to the developing nervous system, particularly in the context of congenital heart disease and/or preterm birth. 

Dr. Calderon's studies include: 

  1. the mechanisms of neurodevelopmental impairments in children and adolescents with critical congenital heart disease after open-heart surgery
  2. the identification of prenatal, neonatal and infant medical risk factors contributing to long-term deficits and 
  3. the study of neurodevelopmental interventions to improve cognitive and behavioral outcomes in this population

Research Background

Dr. Johanna Calderon has a PhD in Pediatric Neuropsychology from Paris Descartes Sorbonne Paris Cite University and a Master's degree in Cognitive Sciences and Psychology from Paris Descartes University.

Publications

  1. Neurocognitive and Psychological Interventions for Adults With Congenital Heart Disease: A Consensus Statement From the Adult Congenital Heart Disease/Neuro 2024 Conference. J Am Heart Assoc. 2026 Jan 20; 15(2):e042921. View Abstract
  2. Prenatal maternal mental health and neurodevelopment in congenital heart disease in France: the neuro-moms CHD multicentre prospective study protocol. BMJ Open. 2025 Dec 23; 15(12):e104889. View Abstract
  3. Early motor outcomes in infants with complex congenital heart disease: the predictive role of NSE and S100B. Pediatr Res. 2025 Sep 24. View Abstract
  4. Design and rationale of "Antecedents and correlates of well-being in young adults with congenital heart disease in the Boston Circulatory Arrest Study (BCAS-adult)". Am Heart J. 2025 Nov; 289:127-137. View Abstract
  5. Evaluating the factor structure of the Wechsler Adult Intelligence Scale, Fourth Edition (WAIS-IV) in adults with congenital heart disease. Clin Neuropsychol. 2025 Oct; 39(7):2021-2032. View Abstract
  6. Neurodevelopmental outcomes of preterm and growth-restricted neonate with congenital heart defect: a systematic review and meta-analysis. Eur J Pediatr. 2024 May; 183(5):1967-1987. View Abstract
  7. Neurological and Psychological Sequelae Associated With Multisystem Inflammatory Syndrome in Children. JAMA Netw Open. 2023 07 03; 6(7):e2324369. View Abstract
  8. Social cognition and behavioral outcomes in congenital heart disease: profiles and neuropsychiatric comorbidities. Child Neuropsychol. 2023 11; 29(7):1041-1063. View Abstract
  9. Prevalence and associated factors of post-traumatic stress disorder in parents whose infants have single ventricle heart disease. Cardiol Young. 2023 Nov; 33(11):2171-2180. View Abstract
  10. Sleep Patterns in Young Children with Congenital Heart Disease. J Pediatr. 2023 01; 252:198-203.e2. View Abstract
  11. Neurodevelopmental and Mental Health Outcomes in Patients With Fontan Circulation: A State-of-the-Art Review. Front Pediatr. 2022; 10:826349. View Abstract
  12. Fetal Brain Volume Predicts Neurodevelopment in Congenital Heart Disease. Circulation. 2022 04 12; 145(15):1108-1119. View Abstract
  13. Quality of Life of Children Born with a Congenital Heart Defect. J Pediatr. 2022 05; 244:148-153.e5. View Abstract
  14. Neurological features in infants with congenital heart disease. Dev Med Child Neurol. 2022 06; 64(6):762-770. View Abstract
  15. Physical activity and aerobic fitness in children with inherited cardiac diseases. Arch Cardiovasc Dis. 2021 Nov; 114(11):727-736. View Abstract
  16. Health-related quality of life and physical activity in children with inherited cardiac arrhythmia or inherited cardiomyopathy: the prospective multicentre controlled QUALIMYORYTHM study rationale, design and methods. Health Qual Life Outcomes. 2021 Jul 28; 19(1):187. View Abstract
  17. Long-Term Neurodevelopmental Outcomes of Children with Congenital Heart Defects. J Pediatr. 2021 Oct; 237:109-114.e5. View Abstract
  18. Neurodevelopmental and psychosocial interventions for individuals with CHD: a research agenda and recommendations from the Cardiac Neurodevelopmental Outcome Collaborative. Cardiol Young. 2021 Jun; 31(6):888-899. View Abstract
  19. Executive functions in children with heart disease: a systematic review and meta-analysis. Cardiol Young. 2021 Dec; 31(12):1914-1922. View Abstract
  20. Randomized Controlled Trial of Working Memory Intervention in Congenital Heart Disease. J Pediatr. 2020 12; 227:191-198.e3. View Abstract
  21. Autism and Congenital Heart Disease: Evidence and Unresolved Questions. Pediatrics. 2019 11; 144(5). View Abstract
  22. Neurotoxicity of general anesthetics in children: evidence and uncertainties. Curr Opin Pediatr. 2019 04; 31(2):267-273. View Abstract
  23. Improving neurodevelopmental outcomes in children with congenital heart disease: protocol for a randomised controlled trial of working memory training. BMJ Open. 2019 02 19; 9(2):e023304. View Abstract
  24. Outcomes Research in Vulnerable Pediatric Populations. J Neurosurg Anesthesiol. 2019 Jan; 31(1):140-143. View Abstract
  25. Working Memory Training: A Promising Intervention? Crit Care Med. 2018 07; 46(7):1199-1201. View Abstract
  26. Neurocognitive and Psychological Outcomes in Adults With Dextro-Transposition of the Great Arteries Corrected by the Arterial Switch Operation. Ann Thorac Surg. 2018 03; 105(3):830-836. View Abstract
  27. Population-based study of cognitive outcomes in congenital heart defects. Arch Dis Child. 2018 01; 103(1):49-56. View Abstract
  28. Cognitive outcomes and health-related quality of life in adults two decades after the arterial switch operation for transposition of the great arteries. J Thorac Cardiovasc Surg. 2017 09; 154(3):1028-1035. View Abstract
  29. Ages and Stages Questionnaire at 3 Years for Predicting IQ at 5-6 Years. Pediatrics. 2017 Apr; 139(4). View Abstract
  30. Neuropsychological and Psychiatric Outcomes in Dextro-Transposition of the Great Arteries across the Lifespan: A State-of-the-Art Review. Front Pediatr. 2017; 5:59. View Abstract
  31. Educational needs of adolescents with congenital heart disease: Impact of a transition intervention programme. Arch Cardiovasc Dis. 2017 May; 110(5):317-324. View Abstract
  32. Psychiatric Disorders in Adolescents With Single Ventricle Congenital Heart Disease. Pediatrics. 2017 Mar; 139(3). View Abstract
  33. Early-Term Birth in Single-Ventricle Congenital Heart Disease After the Fontan Procedure: Neurodevelopmental and Psychiatric Outcomes. J Pediatr. 2016 12; 179:96-103. View Abstract
  34. Executive Function in Patients with Congenital Heart Disease: Only the Tip of the Iceberg? J Pediatr. 2016 06; 173:7-9. View Abstract
  35. Executive function deficits in congenital heart disease: why is intervention important? Cardiol Young. 2015 Oct; 25(7):1238-46. View Abstract
  36. Facial expression recognition and emotion understanding in children after neonatal open-heart surgery for transposition of the great arteries. Dev Med Child Neurol. 2014 Jun; 56(6):564-71. View Abstract
  37. Executive functions development in 5- to 7-year-old children with transposition of the great arteries: a longitudinal study. Dev Neuropsychol. 2014; 39(5):365-84. View Abstract
  38. Use of early remedial services in children with transposition of the great arteries. J Pediatr. 2013 Oct; 163(4):1105-10.e1. View Abstract
  39. Impact of prenatal diagnosis on neurocognitive outcomes in children with transposition of the great arteries. J Pediatr. 2012 Jul; 161(1):94-8.e1. View Abstract
  40. Executive function and theory of mind in school-aged children after neonatal corrective cardiac surgery for transposition of the great arteries. Dev Med Child Neurol. 2010 Dec; 52(12):1139-44. View Abstract

Contact Johanna Calderon

Phone: 857-218-5063
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